Information on the topics listed on this slide will be presented in the lecture.

Responsibilities of principal investigators in Phase I clinical trials involve:
・Requirements of a principal investigator
・Sub-investigators and clinical trial collaborators
・Selection of prospective patients
・Responsibilities toward patients
・Deviation from protocol
・Case report forms
・Adverse drug reports during clinical trials
・Discontinuation of clinical trials

Important personnel in Phase I clinical trial team involve:
・Organization of personnel introduced in the first half
・Clinical trial coordinators
・Nurses and laboratory technicians