Introduction of "Ethical Education Training Contents for Animal Experiments"《講師：Noboru Ogiso》

The contents of the course are designed to be easy to listen to, with each content lasting 15 to 30 minutes. In addition, important items that should be considered for the welfare of laboratory animals, such as the classification of pain levels for animal experiment procedures, establishment of humane endpoints, and anesthesia methods for laboratory animals, are subdivided and explained in detail and with care. We hope you will make effective use of these contents. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download. [ click here for PDF  ] For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp ).

Related Laws and Regulations Related to Laboratory Animals and Animal Experiments《講師：Toshio Imai​》

It goes without saying that analysis using laboratory animals is essential for medical research on various diseases. However, animal experiments must be conducted properly according to certain rules and in accordance with an experiment plan that gives full consideration to animal welfare. In this course, we will proceed to explain the relevant laws, regulations, and guidelines that animal experiment personnel need to understand at a minimum. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Basic Matters Concerning Methods of Animal Experiments, etc.《講師：Kyoko Shioya》

Animal experimentation cannot be done on the spur of the moment. In this course, necessary matters before starting animal experiments will be explained in an easy-to-understand manner. It also explains what to do after the animal experiment is completed. Please read it before starting an animal experiment. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp).

Pain Level Classification and Perioperative Management of Animal Experimental Procedure《講師：Kazuhiro Yamamoto​》

Animal experimenters are obligated to objectively judge the degree of pain experienced by experimental animals as a result of planned experimental procedures, and to take measures to alleviate the pain. Based on the "SCAW classification", which is widely used as a standard in Japan and overseas, we will explain how to judge the degree of pain in experimental animals due to animal experimental procedures, and also explain perioperative management in highly painful surgeries. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Humane Endpoints and Euthanasia in Animal Experiments《講師：Kazuhiro Yamamoto​》

Animal experimenters should discontinue experimental procedures if they determine that an experimental animal is experiencing distress not anticipated in the plan. Humane endpoints are the criteria for discontinuing experimental treatments or euthanizing animals based on symptoms, etc., which are determined at the planning stage. We describe common humane endpoints, as well as a brief description of methods for euthanizing animals to relieve them of intolerable pain. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Fundamentals of Anesthesia for Laboratory Animals​《講師：Tadashi Okamura》

When conducting animal experiments, it is required to minimize the pain and suffering that the animal receives. The use of anesthetics and analgesics is effective in reducing animal pain. Anesthesia and analgesia methods used in experimental animals are reviewed. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Characteristics of Triple Mixed Anesthetic《講師：Tadashi Okamura​》

Triple anesthetics, which are balanced anesthetics, are widely used, mainly in rodents. It has a wide safety margin and is very easy to use, but it is necessary to understand its characteristics when using it in animal experiments. We review the properties of triple anesthetics and illustrate their impact on experimental data with specific examples. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Introduction to Anesthesia for Medium-Sized Animals​(dogs and pigs)​《講師：Kenjiro Konno​》

We will explain an overview of anesthesia, analgesia, and sedation methods for medium-sized animals. These differ depending on the content of animal experiments. A concrete example is given to explain the effect on the experimental data. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Euthanasia Method for Laboratory Animals​《講師：Tadashi Okamura​》

Euthanasia is the act of inducing rapid loss of consciousness and death in experimental animals without pain. Animal experimenters performing euthanasia must be properly trained and select a humane method of euthanasia according to the purpose of the experiment. An overview of internationally accepted methods as described in the “American Veterinary Medical Association (AVMA) Euthanasia Guidelines 2020”.PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Matters Concerning Safety Assurance and Safety Management Related to Animal Experiments, Experimental Animals, Facilities, etc.​《講師：Noboru Ogiso​​》

The Ministry of the Environment's notification, "Standards for the Care and Storage of Laboratory Animals and Alleviation of Pain," calls for ensuring the safety not only of laboratory animals, but also of humans (researchers, engineers, breeders). We will explain specific measures for occupational safety and health, including troubles and near-miss cases, regarding safety assurance and safety management related to animal experiments, laboratory animals, facilities, etc. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Experimental Animal Welfare Efforts ​－Environmental Enrichment (focusing on rodents)－​《講師：Noboru Ogiso​​》

When carrying out daily breeding management and experimental treatments, it is necessary  not only keep the animals clean, but also reduce and adapt to environmental stress. Therefore, we will introduce ideas for improving and enriching the breeding environment so that animals can live healthy and comfortable both physically and mentally. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the Central Secretariat (6nc-educ.jimu@jh.ncgm.go.jp). 

Infectious Diseases in Laboratory Animals《講師：Hideki Tsumura​》

Infectious diseases in experimental animals are a factor that greatly affects animal experiments. It is listed, in the standards for the care and storage of experimental animals and the alleviation of suffering, the 3rd common standard states that "strive to maintain the health and safety of experimental animals" and "perform necessary health management such as prevention of disease". It is the basis of animal experiments that experimental animals are kept healthy and used for experiments. Microbial monitoring for the early detection of infectious diseases in experimental animals is outlined, and the effects of currently prevalent infectious diseases on experiments are explained. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Zoonotic Disease​s《講師：Hideki Tsumura​​》

Zoonotic disease is a general term for infectious diseases that infect humans and animals. In the Standards for the Care and Storage of Experimental Animals and Alleviation of Pain, the 3rd Common Standard states, "Efforts should be made to acquire sufficient knowledge and collect information on common infectious diseases between humans and animals." Zoonotic diseases from laboratory animals are now almost unrecognizable. However, we must learn from past cases and always prepare for zoonotic diseases that may occur in the future. PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp). 

Regulation of Genetically Modified Organisms and Pathogens《講師：Takashi Hamabata​》

Experiments that create and use genetically modified animals, experiments that inoculate animals with genetically modified microorganisms or pathogens, etc. must be conducted appropriately in accordance with laws and guidelines such as the "Cartagena Act". We will explain the points to note in the use, storage, and transportation of genetically modified organisms and pathogens, using specific examples.PDF of the PowerPoint document used in this video is available for download. Click on the following link to download.[ click here for PDF ]For content inquiries, please contact the central office (6nc-educ.jimu@jh.ncgm.go.jp).